Hiv care – Wankanyakla Self Help Group Sun, 19 Sep 2021 16:58:46 +0000 en-US hourly 1 Hiv care – Wankanyakla Self Help Group 32 32 More signs HCV care has suffered during pandemic Sun, 19 Sep 2021 15:35:57 +0000

September 19, 2021

1 minute read

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Barocas does not report any relevant financial information. Please see the study for relevant financial information from all other authors.

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Due to the pandemic-related disruption in hepatitis C care, researchers said thousands of cases will remain unidentified with fewer patients initiating care and reaching SVR.

“The combination of lockdowns and hold orders, healthcare facilities pausing different clinical services and the need to divert resources to COVID-19 have meant that the trajectories of different diseases have been altered. We have seen this happen with services for HIV, malaria and tuberculosis around the world ”, Joshua A. Barocas, MD, associate professor of medicine at the University of Colorado School of Medicine, Healio said.

Judge Barocas et al.  Clin Infect Dis.  2021; doi: 10.1093 / cid / ciab779.

Judge Barocas et al. Clin Infect Dis. 2021; doi: 10.1093 / cid / ciab779.

“We had the hypothesis that the trajectory of HCV in the population would also be altered,” said Barocas. “We thought it was important to understand the possible long-term impact of COVID-19 on the hepatitis C epidemic in the United States. “

Barocas and colleagues used microsimulation to estimate the 10-year impact of COVID-19 disruptions in health care delivery on HCV outcomes, including infections, link to care, onset and onset. end of treatment, cirrhosis and liver-related death.

They modeled hypothetical scenarios consisting of an 18-month pandemic-related hiatus in HCV care from March 2020, followed by varying returns to pre-pandemic screening, linkage and treatment rates through March 2030, and compared them to a counterfactual scenario in which there was no COVID-19 pandemic or disruption of care.

In the scenario where there is no return to pre-pandemic levels of HCV care, researchers calculated 1,060 fewer identified cases, of which only 3% initiate treatment and less than 1% achieve SVR. In addition, 21 additional cases of cirrhosis and 16 additional liver-related deaths per 100,000 people would be reported compared to the “no pandemic” scenario, they said.

Based on these findings, Barocas and colleagues said there needs to be a re-engagement with the HCV epidemic in the United States to overcome the disruption related to COVID-19. Other projects have also shown impacts linked to the pandemic on HCV care.

“The COVID-19 pandemic has caused an unprecedented disruption in the delivery of health services. Vulnerable populations in the United States, including those who are affected and at risk of contracting HCV, are likely to experience worse outcomes as a result, ”said Barocas. “We need to redouble our efforts and commit additional resources to find, link and treat people with HCV. Without it, we risk the HCV epidemic for many years to come. “

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Annual pride event fills Eastman Park in St. Cloud [PHOTOS] Sat, 18 Sep 2021 18:32:25 +0000

ST. CLOUD – Residents of central Minnesota filled Eastman Park this weekend to celebrate peace, love and diversity in the St. Cloud area.

St. Cloud Pride Week continued with pride in the park from 11:00 am to 3:00 pm on Saturday. The annual family event included a variety of local businesses and organizations, food vendors, games and live music.

There was also a puppy parade to raise funds for the Tri-County Humane Society with prizes for the best dressed dogs.

The festivities continue on Saturday night with the annual 21+ drag show at River’s Edge Convention Center and the Pride after-party at the Red Carpet.

St. Cloud Pride 2021 ends Sunday with the second annual Pride Parade in downtown St. Cloud at 2:00 PM. block to 1st Street North.

St. Cloud Pride was founded in 2010 and works to raise awareness of homophobia and transphobia, as well as provide education, resources and support to members of LGBT + communities and the Greater St. Cloud.

KEEP WATCHING: Here Are 33 LGBTQ + Charities That Need Your Donation

Bucket List Attractions in Minnesota – Must See

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Tallahassee residents mobilize to raise awareness about HIV Thu, 16 Sep 2021 22:17:36 +0000

TALLAHASSEE, Fla. (WTXL) – It’s a disease that affects one in 172 people here in the Big Bend.

“It completely changed my life. I was diagnosed in 1999.”

Tracy has been HIV positive for over two decades. It is a virus that wreaks havoc on your immune system and your mental will.

“I went through all the emotions that come with it. I tried to kill myself and do it faster.”

Now she spends her life giving back.

“I changed, quit drinking and using drugs, and started volunteering with AIDS agencies that help people living with HIV.”

One of those organizations is Big Bend Cares.

“What we do is help people affected or affected by HIV or AIDS.”

Stephanie Schwartz is the Director of Development for Big Bend Cares. Schwartz and hundreds of neighbors prepare for the annual Tallahassee AIDS Walk. The Walk – raising awareness and funding for families and friends affected by the virus. A virus that kills nearly 16,000 people in the United States each year.

“He is immunocompromised, HIV is as well as COVID. So all of our customers are doing their best. “

The money needed to buy drugs and supplies can also be overwhelming. Big Bend Cares and other organizations are trying to ease this burden

“Over 33% of Care Point customers don’t have the insurance that we served last year. The money therefore goes to medical care. The money goes to non-perishable food.

For Tracy, it means a lot to see the community giving back.

“It’s good to know that… you are not alone. I am not alone in this fight.”

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POC diagnostics market worth $ 81.37 billion at 9.4% per Thu, 16 Sep 2021 06:57:43 +0000

Pune, India, September 16, 2021 (GLOBE NEWSWIRE) – The world POC Diagnostics Market The size is expected to gain ground reaching $ 81.37 billion by 2028 while posting a 9.4% CAGR between 2021 and 2028. This information is published by Fortune Business Insights in a report titled “POC Diagnostics Market, 2021 -2028 ”. The report further mentions that the market amounted to USD 34.49 billion in 2020. Factors such as the increasing prevalence of chronic diseases and the increasing emphasis on the introduction of advanced test kits will promote the growth of the market . According to data from the United Nations Program on HIV / AIDS (UNAIDS), in 2019, approximately 38 million people were diagnosed with HIV / AIDS.

The outbreak of the coronavirus has put massive economic pressure on industries in various countries. We understand that this health emergency has had a negative impact on various sectors around the world. Growing support from governments and several companies can help fight this highly infectious virus. Some industries are struggling and others are thriving. It is estimated that almost all sectors are affected by this pandemic.

Important developments in the POC Diagnostics Market industry include:

june 2020 – Celltrion Group launched a SARS-CoV-2 point-of-care antigen diagnostic kit. Launch Expected to Help Solidify Position in Managing and Treating COVID-19 Diagnosis and Treatment Globally

Request a sample copy of the research report:

What does the report include?

The market report comprises detailed qualitative and quantitative analysis of the market and focuses on crucial aspects such as materials, major companies, applications, and products. In addition, the report offers an overview of the latest trends and highlights the main developments in the industry. The report further includes historical data and revenue growth forecast at global, regional and country level. It analyzes the latest industry dynamics and opportunities to impact the market growth between 2021 and 2028.

Click here to learn about the short and long term impact of COVID-19 on this market.

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Increased focus on launching innovative diagnostic devices to propel market growth

The increasing number of chronic diseases such as infectious diseases, diabetes, HIV, etc., is pushing several pharmaceutical companies to introduce innovative test kits. This should stimulate demand for the product. For example, in June 2019, Abbott launched the Afinion HbA1c Dx test, a one-of-a-kind point-of-care test approved by the U.S. Food and Drug Administration (FDA) to detect diabetes. The continued efforts by major companies to develop advanced POC kits are therefore expected to contribute to the growth of the global POC diagnostics market during the forecast period.

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North America remains dominant; Growing adoption of advanced POC kits to promote growth

Among all regions, North America is expected to remain at the forefront and hold the highest position in the market for years to come. This is due to the increasing adoption of advanced point-of-care (POC) diagnostic kits to detect infectious diseases in the region during the forecast period. North America was worth $ 14.10 billion in 2020.

Europe is expected to occupy the second position in the market during the forecast period. This is due to the growing investment in the development of point-of-service diagnostics (POC) in countries like Germany, Spain and France. For example, in November 2019, Linear Diagnostics secured an investment of $ 2.6 million to develop an advanced POC optical diagnostic test platform to detect sexually transmitted diseases.

The list of manufacturers in the POC Diagnostics market includes:

  • Hoffmann-La Roche SA
  • Thermo Fisher Scientific Inc.
  • Abbott Laboratories
  • Quest Diagnostics Incorporated
  • Comics
  • bioMérieux SA
  • Cardinal Health, Inc.
  • Mesa Biotech
  • Cepheid
  • Trinity Biotech
  • Quidel Corporation
  • Bio-Rad Laboratories inc.
  • Other players

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Global segmentation of the POC diagnostics market:

  • introduction
    • Market scope
    • Market segmentation
    • Market methodology
    • Definitions and assumptions
  • Abstract
  • Market dynamics
    • Market factors
    • Market constraints
    • Market opportunities
  • Global POC Diagnostics Market Analysis, Outlook and Forecast, 2017-2028
  • Main conclusions / Summary
  • Market analysis, information and forecasts – by product
    • Blood glucose monitoring
    • Infectious diseases
    • Cardiometabolic diseases
    • Pregnancy and infertility tests
    • Hematology tests
    • Others
  • Market analysis, information and forecasts – by end user
    • Hospital bedside
    • Doctor’s office laboratory
    • Retail and emergency care clinics
    • Home care / Self-test
  • Market analysis, information and forecasts – by geography
    • North America
    • Europe
    • Asia Pacific
    • Latin America
    • Middle East and Africa

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  • Details such as revenue, market share, strategies, growth rate, products and their pricing by region / country for all major companies
  • Details regarding prevalence, incidence, number of patients, distribution of patients, average price of treatment, etc.
  • Number of end-user installations by region / country and average annual spend or device purchases by type of end-user installations
  • Number of procedures and average price of procedures
  • Replacement rate and pricing of capital goods
  • Market dynamics versus target market – Drivers, constraints, trends and opportunities
  • Market and technology trends, new product developments, product pipeline.

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AHF mourns the passing of Reverend Carl Bean | Business Thu, 09 Sep 2021 01:19:37 +0000


AIDS Healthcare Foundation (AHF), the largest global AIDS organization today and which began its journey providing care and services to HIV / AIDS patients 35 years ago in Los Angeles providing palliative care for people dying of AIDS, today mourned the passing of a famous AIDS activist and openly gay black preacher, the Reverend Carl Bean, an icon in the fight against stigma and discrimination in communities of color.

At the start of the AIDS pandemic, AHF named one of its three AIDS hospices in honor of Reverend Bean. AHF operated the 25-bed Carl Bean House in the West Adams district of south Los Angeles from 1992 until February 2006, when it ceased providing palliative care services at the site due to declining needs. through life-saving antiretroviral drugs and corresponding funding cuts for end-stage AIDS care. When it closed, it was the only 24-hour AIDS hospice and residential HIV / AIDS nursing facility in Los Angeles and more than 3,000 people lived – and died there.

“Archbishop Carl Bean has been my brother in struggle for the past 35 years. We walked through the fire together in the height of pain and death. Whatever pressures might have divided us, we have always been there for each other, ”said Michael weinstein, president of the AHF. “An irreplaceable part of our history is taken away with his death. However, a small part of his legacy of service lives on at the Carl Bean House, which began as a hospice and still serves as a sacred land and place of healing today. Rest in the peace you have richly deserved dear friend and comrade. “

Today, a state-of-the-art AHF healthcare center is located on Adams Boulevard, just west of Western Avenue. In addition, the Carl Bean campus is also home to In The Meantime Men’s Group, an organization that “… has been at the forefront of creating an environment that supports, empowers and educates black, gay, gay and bisexual men in Los Angeles County.”

According to the Los Angeles Sentinel, “Archbishop Carl Bean started the Minority AIDS Project (MAP) in Los Angeles. MAP was the first community-based HIV / AIDS organization that focused on the prevalence of HIV / AIDS transmission in the black community at a time when the disease was considered relatively new.

About AHF

AIDS Health Foundation (AHF), the world’s largest AIDS organization, currently provides healthcare and / or medical services to more than 1.6 million people in 45 countries around the world in the United States, Africa, Latin America / Caribbean, Asia / Pacific region and Eastern Europe. To learn more about AHF, please visit our website:, find us on Facebook: and follow us on Twitter: @helpful

See the source version on

CONTACT: Ged Kenslea, Senior Director, Communications for AHF +1.323.791.5526

MW Imara Canada, AHF National Director, Communications and Community Engagement, +1.770.940.6555 mobile



SOURCE: AIDS Healthcare Foundation

Copyright Business Wire 2021.

PUB: 08/09/2021 21:19 / DISC: 08/09/2021 21:19

Copyright Business Wire 2021.

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Taliban special forces brutally end women’s protest Sat, 04 Sep 2021 20:35:06 +0000 Bloomberg Quicktake: Now released this video clip, titled “Taliban Special Forces Brutally End Women’s Protest” – below is their description.

Camouflage-clad Taliban special forces fired into the air on Saturday, bringing a brutal and frightening end to the latest protest march in the capital by Afghan women demanding equal rights for the new leaders.

Also on Saturday, the head of the powerful Pakistani intelligence agency, which has disproportionate influence over the Taliban, paid a surprise visit to Kabul.

Taliban fighters quickly captured most of Afghanistan last month and celebrated the departure of the last US forces after 20 years of war. The insurgent group must now rule a country ravaged by war and heavily dependent on international aid.

The women’s march – the second in as many days in Kabul – began peacefully. Protesters laid a wreath outside the Afghan Ministry of Defense to honor Afghan soldiers who died fighting the Taliban before heading to the presidential palace.

“We are here to obtain human rights in Afghanistan,” said Maryam Naiby, a 20-year-old protester. “I love my country. I will always be here.”

As the protesters’ cries grew louder, several Taliban officials rushed into the crowd to ask them what they wanted to say.

Flanked by other protesters, Sudaba Kabiri, a 24-year-old university student, told her Taliban interlocutor that the Prophet of Islam had given women rights and they wanted theirs. The Taliban official promised women would be granted their rights, but the women, all in their early twenties, were skeptical.

As the protesters reached the presidential palace, a dozen Taliban special forces rushed into the crowd, firing in the air and scaring the protesters away. Kabiri, who spoke to the Associated Press, said they also fired tear gas.

The Taliban have promised an inclusive government and a more moderate form of Islamic rule than when they last ruled the country from 1996 to 2001. But many Afghans, especially women, are deeply skeptical and fear a retreat. rights acquired over the past two decades. .

For much of the past two weeks, Taliban officials have held meetings among themselves, amid reports of differences between them. Early Saturday, the powerful neighboring Pakistani intelligence chief General Faiez Hameed paid a surprise visit to Kabul. It was not immediately clear what he had to say to the Taliban leadership, but Pakistani intelligence has a strong influence over the Taliban.

The Taliban leadership was headquartered in Pakistan and was often said to be in direct contact with the powerful Inter-Services Intelligence agency. Although Pakistan has consistently denied providing military aid to the Taliban, the accusation has often been made by the Afghan government and Washington.

Faiez’s visit comes as the world waits to see what kind of government the Taliban eventually announce, seeking one that is inclusive and ensures the protection of the rights of the country’s women and minorities.

The Taliban have pledged a broad-based government and have held talks with former President Hamid Karzai and former government negotiator Abdullah Abdullah. But the makeup of the new government is uncertain, and it was unclear whether die-hard ideologues among the Taliban would prevail – and whether the dreaded setbacks by female protesters will occur.

Taliban operatives on Saturday whitewashed murals that promoted health care, warned of the dangers of HIV and even paid tribute to some of Afghanistan’s iconic foreign contributors, such as anthropologist Nancy Dupree, who single-handedly chronicled Afghanistan’s rich cultural heritage. It was a disturbing sign of attempts to erase memories of the past 20 years.

Bloomberg Quicktake: now YouTube channel

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SLO County Jail Report Details Abuse, Violence Wed, 01 Sep 2021 23:05:46 +0000
September 1, 2021

An inmate held in a special type of restrictive housing at SLO County Jail.


A new report on the San Luis Obispo County Jail chronicles abuse ranging from punching inmates to denial of medical treatment – resulting in deaths and miscarriages in prison – as it details accounts of brutality, violations of civil rights; and failures of county administrators to properly train members of Parliament or to report use of force.

The August 31 report marks the culmination of the US Department of Justice’s three-year investigation into civil rights violations at the county jail. Investigators determined that county staff violated the constitutional rights of inmates by using excessive force and failing to provide constitutionally adequate medical and mental health care.

Between January 2012 and June 2020, 16 detainees died in custody, many in questionable circumstances.

On January 22, 2017, Andrew Holland, 36, died of a pulmonary embolism in his lungs after being tied in a restraint chair with his legs and arms shackled for more than 46 hours, which has been exclusively reported by CalCoastNews after a year. lengthy investigation into allegations of ill-treatment of detainees.

Ten days earlier, a judge had ordered Holland to be put on medication against his will and sent to a mental institution, but county staff did not comply.

While in the chair, a blood clot formed in Holland’s leg. When Holland was released from the chair, the blood clot traveled to his right lung, causing a pulmonary embolism and his death. He spent his last minutes writhing on the floor of a cell as MPs watched him through the glass cell door.

Shortly after Holland’s death, the FBI opened a criminal investigation into a series of county jail deaths. This investigation appears to be ongoing.

In October 2018, the Justice Department opened a civil rights investigation which found the county failed to provide adequate medical and mental health care to detainees, prevented excessive use of force, stopped submitting inmates for extended periods of restrictive housing and to comply with the Americans with Disabilities Act.

The report details specific cases of alleged violations of civil rights. These allegations include cases of spraying immobilized detainees with pepper spray, pulling detainees by the hair, slamming detainees against walls and detaining detainees for long periods of time.

The following cases are cases of excessive force as described in the report of the Ministry of Justice:

“In December 2018 AK (names of detainees withheld) shouted at MPs while he was safe in a caged area. Three deputies unlocked the door and AK calmly exited. An assistant grabbed the AK without resistance from behind and pushed him headfirst against a wall, causing him to bleed. The deputy lied about the force in the incident report, stating that AK had pulled away and “fell forward” towards the wall.

“In May 2018, AM allegedly kicked his cell door. The deputies opened his cell and lifted him by his elbows after handcuffing his hands behind his back and dragged him at least 30 feet to a wheelchair. There was no documented reason why staff did not bring his wheelchair to him instead of dragging him to the chair.

“AO allegedly cursed two deputies from inside his cell. The senior assistant grabbed the prisoner by the neck and repeatedly pushed him against a wall and on the floor even though AO came out of his cell with his hands behind his back. The first assistant then
pulled AO to his feet and escorted him into the “chicken wing” cargo hold while handcuffed.

“The senior assistant then inserted his right thumb and applied pressure to the soft tissue under AO’s jaw while waiting for a door to open even though AO was handcuffed and obeyed. More than a dozen guard officers watched and followed the senior assistant as he escorted AO in this manner – apparently abandoning their posts – but no one intervened.

“In an incident in December 2018, a group of six MPs participated in a teardown, at least three of whom used their bodies to pin the AU face down. Then, after the MPs appeared to have the AU under control on the ground, one of the MPs slowly released his pepper spray and – about a foot from the AU’s face – sprayed it in his eyes.

An inmate at the SLO County Jail in WRAP on January 17, 2018.

“In an incident in December 2016, a total of 11 MPs and two sergeants were involved in a teardown of AV in which they hit him four times, including at least two blows to the head, to” win [his] compliance ”, then began to put him in a WRAP, possibly compromising his circulation. After partially immobilizing AV in the WRAP, duty staff discovered he was unconscious and not breathing, necessitating emergency hospitalization.

In the months following Holland’s death, the county made several statements regarding plans to improve conditions, training and law enforcement in the prison. But inmates continued to die while staff refused or provided inadequate medical care, according to the report.

The report also describes cases of inadequate medical care, including:

On April 13, 2017, Kevin Lee McLaughlin, 60, of San Luis Obispo, died in SLO County Jail of a heart attack. McLaughlin suffered from hypertension, but prison staff did not provide an “adequate medical assessment when he entered detention, did not perform any laboratory tests or examinations, or monitor his condition in any way, and prescribed him high doses of ibuprofen, a drug that the FDA says can lead to heart attacks in people with high blood pressure.

“On the morning of his death, McLaughlin complained of pain in his left shoulder and arm, numbness and tingling, wetness and chest pain on his left side, yet the prison medical staff refused. his requests to be sent to the hospital. After noticing that McLaughlin’s breathing was abnormal, an assistant walked away and called the medics, and did not return for five minutes, after which McLaughlin stopped breathing and was unresponsive.

On November 27, 2017, Russell Alan Hammer, 62, who suffered from memory problems, died of deep vein thrombosis after being taken to the prison medical center.

Hammer suffered from Parkinson’s disease and suffered from auditory hallucinations and paranoia while in detention. “Upon his return to prison, he was kept in solitary confinement for over two weeks. The prison ignored her complaints about weight loss and weakness.

The report determined that detainees are “at significant risk of serious harm as a result of inadequate medical care”. Prisoners with life-threatening illnesses or major medical problems are often refused medication or treatment. Several pregnant inmates miscarried while county staff denied them adequate medical treatment.

Here are some examples from the report of failure to provide medication or appropriate care:

“LL, who was admitted to prison in April 2019, did not receive any HIV medication during her first week in detention. Then the prison started providing her with only one of the three drugs she was taking to manage her HIV. It was the only medication she received during the week before her release, and during that week she did not even receive this medication for three consecutive days. Receiving only one of the three HIV drugs creates a high probability of developing resistance to that drug, which is extremely dangerous. “

In February 2019, NN “reported abdominal pain and said she had just found out that her sex partner had gonorrhea. She was tested for it, but there was a three day delay in sending the labs and the positive results did not return for five days, when the prison began treating her for gonorrhea. Two days later, the prison took a pregnancy test, which came back positive, but she did not have an obstetrician appointment. Five days later, she reported vaginal bleeding to medical staff, who ordered an obstetrics referral two days later. “

Even though NN was suffering from vaginal bleeding, obstetric referral was not followed and she miscarried.

Sheriff Ian Parkinson

In its response to the report, the SLO County Sheriff’s Office confirmed the issues and concerns raised, but criticized the Justice Department for “ignoring the many corrective actions taken by the Sheriff’s Office.” over the past three years, according to a press release.

“The Sheriff’s Office has worked cooperatively with the Department of Justice for the past three years to investigate shortcomings and determine appropriate improvements to ensure our prison facility is fully compliant with federal law,” the Sheriff said. Ian Parkinson in a press release. “We are pleased with our progress so far and will continue to work diligently to provide a safe and secure prison facility.”

The county has 49 days to comply with at least 45 corrective actions identified in the report, or the United States attorney general can initiate legal action to force the county to correct its deficiencies.

“In listing these remedies, we note that during our investigation, the prison made changes to its staff, policies and procedures. We have taken these changes into account, but we find that they are insufficient to protect detainees from the harm identified, ”according to the report.

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‘I wasn’t getting better’: Pennsylvania woman endures long-term battle with COVID | Mon, 30 Aug 2021 07:52:00 +0000

More than a year and a half after contracting COVID-19, Andrea Berlin is feeling almost completely normal.

The Fox Chapel-turned-London native said she fell ill with the virus in March 2020 – at the start of the pandemic by most standards – and she believes she likely picked it up on the tube before the country does not hang.

“I overcame this acute stage. The fever was gone, but I ended up with fatigue, headaches, almost Parkinson’s-like body tremor, heart palpitations – fatigue was the worst, ”Berlin told the Tribune-Review this this month.

The Fox Chapel Area High School graduate was captain of the tennis team. She is now working as a recruiter in London. Her father, a neurologist, has offices throughout the Alle-Kiski Valley.

When it comes to COVID-19, the “recovered” statistic often translates simply as “survived”.

Many people then report a myriad of symptoms that persist for weeks, months and, at this point, years. Many studies have attempted to get a more precise picture of the exact number of people with long-covid.

Estimates vary as to the number of covid-19 survivors who suffer from long-lasting symptoms. In the United States, some have pegged the numbers between 10% and 30%. A University of California-Davis study estimated that up to a quarter of COVID patients suffer from “long-term” symptoms.

Often referred to as “long-haul COVIDs,” these are people who exhibit persistent symptoms – some they did not even have during acute illness. Others fell seriously ill and survived. Others still had mild or no symptoms of the virus.

Yet, once their system is no longer infected, they report chronic fatigue, chronic pain that they’ve never had before, the same shortness of breath and heart palpitations that have plagued the virus itself. They suffer from brain fog and depression, and many cannot tolerate much if any level of exercise.

COVID is gone, and yet it continues.

“Even after a year and a half, we don’t know much,” said Dr. Alison Morris, division chief of pulmonary, allergic and critical care medicine at the University of Pittsburgh.

What doctors and medical experts know, she said, is this: People have symptoms that take much longer to resolve than the virus itself. The syndrome does not discriminate, in that it affects people who are critically ill and hospitalized with COVID as well as those with milder cases.

“There is a very wide variety of symptoms that span pretty much every organ system,” said Morris, who also heads UPMC’s COVID-19 recovery clinic. “Some people come in mainly with fatigue, muscle aches and brain fog. Some people come with difficulty breathing or having difficulty exercising. Some people come with low blood pressure and a racing heart.

“It’s really a fairly variable syndrome.”

The Centers for Disease Control and Prevention lists more than a dozen possible symptoms experienced by long-haul COVIDs.

For Berlin, his acute illness was not benign. Twice in the three or four weeks she was ill, she was taken to an ambulance with chest pain and heart palpitations. For almost a month, she suffered from an almost constant fever, feeling too sick to sleep, heart palpitations and shortness of breath.

“It was like everyone was saying it was a two week illness and you would be better,” she said, “but I was not getting any better.”

As the fever subsided, she found herself with constant fatigue, a headache and a body tremor which she compared to Parkinson’s disease. Fatigue, she said, was the worst long-term persistent symptom.

“I had to lie down most of the day otherwise I would feel worse the next day,” she said, noting that she was completely unable to take care of her 7-year-old daughter and her twins. of 3 years.

She went from specialist to specialist, tried acupuncture and some 30 different supplements, osteopathy and psychiatry.

“I saw so many doctors, and they all said, ‘Rest, take your rhythm, it will be better, you just have to rest during this,” “said Berlin.

Dr Tariq Cheema, director of the pulmonary care, intensive care, sleep and allergy division at the Allegheny Health Network, said that at the start of the pandemic, the main focus was on keeping people alive. .

“A lot of the attention, time and energy was spent with the inpatients, and rightly so, because they were sick and people were dying,” said Cheema, chief medical officer of the AHN recovery clinic. Post COVID-19.

In the UK, a study from Imperial College London titled Real-time Assessment of Community Transmission (REACT) surveyed more than 500,000 people, more than 76,000 of whom said they had COVID. The researchers asked about 29 different symptoms, ranging from fatigue and brain fog to dizziness and heart palpitations.

More than a third said they had experienced at least one symptom for 12 weeks or more, and 15% said they had had three or more symptoms for at least that long. The study took place between September 2020 and February.

“I can really be part of my children’s days”

Berlin was not improving.

She said she took comfort on social media, finding groups of other so-called long haulers online, sharing and comparing symptoms and advice. It was on social media that she first came across the name of Dr Bruce Patterson.

“I wasn’t really improving and was getting so desperate,” she said. “I was like, ‘Oh, a doctor is really trying to figure it out.'”

She contacted Patterson, a former senior virologist at Stanford University who spent the 1980s and 1990s working in HIV research.

During the first months of the pandemic, Patterson’s company was working on therapeutic trials in the treatment of COVID-19.

“I noticed during the 60-day follow-up and the 90-day follow-up that these patients were improving, these patients were released from the hospital, but without any stretch of the imagination where they were immunologically normal,” Patterson said. .

He used machine learning to analyze blood samples and says the analysis developed an algorithm to identify immunologic profiles specific to long-haul people.

In summary, he said, his research indicates this: A specific type of white blood cell can carry COVID proteins for months or years after the initial infection – but there is no sign of a virus. active.

The only role of these specific white blood cells, called monocytes, is to “patrol the blood vessels,” as Patterson puts it, and that includes crossing the blood-brain barrier. They have a propensity to bind to blood vessels. Because there is still a covid protein that sticks together when they bind together, it causes inflammation.

This inflammation, he postulates, can lead to chronic fatigue, brain fog, exercise intolerance and the myriad of other symptoms some suffer in the weeks and months following recovery from Covid. .

Patterson’s treatment consists of two steps: preventing these cells from migrating with a class of drugs called CCR5 antagonists, and preventing them from binding to blood vessels using a class of drugs used to lower cholesterol called statins.

“If they can’t bind together, they die, so these cells will eventually die,” Patterson said.

Patterson said his company works with around 100 physicians across the country, although he also works with patients of primary care physicians. He said they have coverage in case a patient doesn’t have PCP or their PCP “hasn’t really accepted what we’re trying to do.”

Among that network of doctors is Dr Elliot Michel, a neurologist in private practice and a staff member at Allegheny Valley Hospital in Harrison – and the father from Berlin.

“They can’t do the things they used to do anymore,” he said of the long-distance patients he sees. “This is really their main complaint. They want to go back to what they were, and they can’t figure it out.

For Berlin – whose treatment consisted of an antiparasitic drug, an antiviral drug for HIV, a low dose of steroids, and an antidepressant to help reset her system – that meant spending real time with her. children.

“The best thing is that I can actually be part of my children’s days,” she said. “Instead of lying on the couch watching them play, I got to play with them and I feel like I’m a mom again.”

She said she almost returned to full-time work and felt like she had regained her identity.

“Don’t accept that this is how you are going to be for the rest of your life. Keep looking for answers and help, ”she said. “Don’t feel guilty for focusing on yourself and your own recovery. “

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U of M researchers study how immunocompromised youth respond to vaccines Sat, 28 Aug 2021 03:23:18 +0000

Dr Kline is the local lead investigator for the study, which focuses on people aged 18 to 29.

“I think young people have a lot of social contact,” said Dr Kline. “As we know from data from our local health department, this is actually the age group that has the highest rates of COVID-19.”

His team hopes to recruit 150 young people who have not received a vaccine or tested positive for COVID-19. Participants do not need to be students at the University.

Those who wish to be vaccinated will be randomly selected to either receive Moderna vaccines immediately or receive the standard of care, meaning they can choose to be vaccinated at any time.

“They can access it on their own, if they have not been vaccinated four months after the start of the study, they will also receive the Moderna vaccine,” said Dr Kline. “Then there is a third group of participants who do not want to be vaccinated and yet are ready to participate. “

The third group will not receive a vaccine.

All participants will be asked to take periodic blood samples and daily nasal swabs over a period of four to five months.

If anyone is positive, the research team will endeavor to collect samples from a network of their close contacts.

“I really hope to know how likely it is that people who have been vaccinated will be infected first versus those who have not,” she said. “How much virus is in their nose?” […] Even if you have an asymptomatic infection, how likely are you to pass it on to others?

The trial is being conducted through the COVID-19 Prevention Network (CoVPN), which hopes to recruit 18,000 people across the country.

“The virus is transmitted differently, in different parts of the country, at different times,” said Dr Kline. “As we saw this summer, some of the most important transmissions were in the South, for example, but last fall Minnesota was sort of one of the highest sites in the country and it There will therefore be these seasonal variations in these different regions. I think it’s important to have representation in all the different regions.

With the delta variant, she also expects them to see more cases of transmission.

The new strain of the virus is also affecting another study from the University of Minnesota School of Medicine.

“Delta has definitely thrown a wrench into things,” said Dr. Amy Karger, a clinical pathologist at the University of Minnesota School of Medicine and M Health Fairview.

Dr. Karger studies the immune response to vaccines. This is a national study sponsored by the Serological Sciences Network (SeroNet), which is “a major component of the National Cancer Institute’s response to the COVID-19 pandemic,” according to the University.

His research focuses on how people with weakened immune systems respond to all vaccines.

“We were specifically tasked with examining three immunocompromised populations – HIV patients, transplant patients and patients with a history of cancer,” said Dr. Karger. “Part of the reason we chose the groups we created, we thought there was excellent subspecialty care in these areas of cancer, transplantation and HIV here at the University. from Minnesota and we knew a lot of patients come here for this care. ”

Registration began in June with participants who had not yet received a vaccine. The team recruited people with both weakened and normal immune systems to compare the two groups.

“We try to measure samples one to three months after vaccination, that’s sort of when you expect the immune response to be at its peak, and then we want to track it about every six months. months to see its decline over time, ”explained Dr. Karger.

The study will last two years.

“We’ve just started looking at our preliminary data, we haven’t published anything yet, but it’s certainly showing up in our cohorts so far, some people don’t have as good an immune response as others,” said Dr. Karger. . “We’re really going to spend the next month or two taking a more in-depth look at this data to try to determine what are the contributors to a poor immune response to the vaccine.”

She said research is important in determining how to move forward with vaccinations.

“I think the ultimate goal is if we can understand why people are not responding, maybe we can modulate some of these risk factors or treat them or suggest other vaccination strategies,” she said. declared.

The team is now adding another group of participants to accommodate the changing recommendations. They are looking for people who are immunocompromised, vaccinated and who will receive their third injection.

“It really gives us the opportunity to recruit a whole new batch of participants now that people are getting the third dose,” Dr. Karger said. “We would like to be at the forefront of determining the quality of the response we will get from this additional vaccine.”

To register for Dr. Karger’s study, click here.

To register for Dr. Kline’s study, click here.

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Mississippians living with HIV get transplant options near them Thu, 26 Aug 2021 22:19:40 +0000

JACKSON, Mississippi (WJTV) – For Mississippians living with HIV, organ failure caused by the rigors of their illness can be far more deadly than the infection they are living with.

Executives at the University of Mississippi Medical Center (UMMC) in Jackson said many patients have had to travel out of state for transplants because their HIV or AIDS status requires a different level of expertise. Now, they can receive life-saving kidneys at UMMC, which offers the state’s only organ and bone marrow transplant program.

Dr Prakhar Vijayvargiya and Dr Zerelda Esquer Garrigos, both Assistant Professors in the Division of Infectious Diseases of the Department of Medicine, will work in conjunction with the UMMC transplant team to manage the care of this patient population prone to the infections.

“Patients living with HIV are in an immunosuppressed state and the management of immunosuppressive drugs and HIV will require dedicated training,” said Dr. Pradeep Vaitla, Medical Director of Kidney and Pancreatic Transplantation. “You need someone trained in this area to manage these patients, and that’s what these two people bring to the table.

Garrigos and Vijayvargiya will also manage the pre- and post-transplant care of non-HIV-positive patients who received a kidney from a donor infected with hepatitis C. Previously, hepatitis C patients received transplants at UMMC, but patients not infected with hepatitis did not receive an organ from a donor positive for hepatitis C.

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