Fred Hutch and partners supplement restructuring, zinc and the immune system – and the use of cord blood transplants to treat leukemia and HIV

Newswise – SEATTLE – April 6, 2022 – Below are summaries of recent research results from the Fred Hutchinson Cancer Research Center and other news.

If you’re covering the American Association of Cancer Research Annual Meeting, April 8-13, check out our list of Fred Hutch Highlights for the AACR and contact [email protected] to help you arrange interviews with experts.

Fred Hutch and his partners are restructuring

Fred Hutchinson Cancer Research Center, Seattle Cancer Care Alliance, Seattle Children’s and UW Medicine Complete partnership restructuring Fred Hutch and his partners Seattle Cancer Care Alliance (SCCA), Seattle Children’s and UW Medicine have completed the restructuring of their longstanding relationship. The result is the formation of the Fred Hutchinson Cancer Center, a unified center for adult cancer research and care. The Fred Hutchinson Cancer Center unites Fred Hutch and SCCA into one independent, not-for-profit organization that is also a clinically integrated part of UW Medicine’s and UW Medicine’s cancer program. We will continue to be known as the “Fred Hutchinson Cancer Research Center” until the new visual branding is rolled out later this year.

Research against cancer

Testing cord blood transplants as a cure for leukemia and HIV A new multi-site clinical trial led by Drs. Fred Hutch. Filippo Milano and Hans-Peter Kiem aim to recruit 10 patients with advanced leukemia who are also living with HIV. As a treatment for their cancer, patients will receive transplanted stem cells from cord blood. Since the cord blood in this trial will come from donors with rare genes that confer resistance to HIV, the hope is that the procedure will also give them immunity to HIV.

Science Says: Comedian, researchers tackle tough topics At the Science Says virtual community event, Fred Hutch President and Director Dr. Thomas J. Lynch and panelists Dr. Rachel Issaka, Dr. Michele Andrasik and comedian Trevor Noah spoke about the improvement health care equity and colorectal cancer awareness screening and partnering with diverse communities around COVID-19 vaccine clinical trials.

Immunology

How Zinc Boosts the Immune System In a new study published in late March in the scientific journal Blood, Fred Hutch scientists, led by immunologist Dr. Jarrod Dudakov, revealed two different ways the mineral zinc supports immunity. Using mice, the team discovered that zinc is necessary for the development of a specialized type of immune cell and prompts a critical immune organ to regenerate after damage. Dudakov’s tweet explains how he came to study zinc and the immune system.

COVID-19[feminine

Dernières recherches de Fred Hutch sur COVID-19 Si vous souhaitez en savoir plus sur cette recherche, veuillez contacter : [email protected]

Awards and other notable stories

Dr. Denise Galloway elected Fellow of the American Association for Cancer Research Academy Dr. Denise Galloway joined 255 other scientists as newly elected members of the Academy of the American Association for Cancer Research. Galloway’s pioneering work on virus-like particles and the link between HPV and cervical cancer paved the way for the human papillomavirus cancer vaccine. His research into how certain viruses promote cancer has allowed him to develop a diagnostic test to predict the recurrence of the deadly skin cancer, Merkel cell carcinoma.

Dr. Michael Linenberger honored for his contribution to apheresis medicine Dr. Michael Linenberger has received one of the highest honors in the field of apheresis, the medical subspecialty that uses automated methods to separate blood components for therapeutic manipulation or for use in transfusion, cell transplantation and treatments. The American Society for Apheresis, or ASFA, Presidential Award recognizes Linenberger’s career-long contributions to this field, which is a cornerstone of support for donors and patients involved in blood stem cell transplantation. and cell immunotherapy against cancer.

Spotlight on Science Science Spotlight is a monthly installment of articles written by Fred Hutch postdoctoral fellows that summarize new research papers by Hutch scientists. If you would like to know more or discuss these topics, contact: [email protected]

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At the Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists research new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other diseases potentially fatal. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch is home to the nation’s first National Cancer Institute-funded cancer prevention research program, as well as the Women’s Health Initiative’s Clinical Coordinating Center and International Headquarters. of the HIV Vaccine Trials Network and the COVID-19 Prevention Network.

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