Patients with HIV are at higher risk of cardiac arrest: study | Health


A recent study looked at the risk of heart failure in people living with HIV and how that risk varies by age, sex, race and ethnicity.

A new study has found that people living with HIV are at greater risk of developing heart failure than people without HIV.


The research, published in Mayo Clinic Proceedings, is one of the largest studies to study the risk of heart failure in people living with HIV and how that risk varies by age, sex, race and location. Ethnicity.

“Cardiovascular disease has been a significant concern for people living with HIV for many, many years,” said lead study author Michael J. Silverberg, PhD, MPH, Kaiser HIV researcher and epidemiologist. Permanente Division of Research. “Most of the research in this area has focused on the risk of stroke and heart attack. With this study, we now see that the cardiovascular impacts for people living with HIV extend to phasing conditions. such as heart failure. “

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Silverberg and his colleagues identified 38,868 HIV-positive people who were members of Kaiser Permanente between 2000 and 2016 in one of 3 regions: Northern California, Southern California, and Mid-Atlantic States.

Then, they matched each person with up to 10 Kaiser Permanente members from the corresponding region who were the same age, gender, and race but did not have HIV; this group consisted of 386,586 people. Finally, they identified people in both groups who had developed heart failure during follow-up.

The study found that people with HIV were 68% more likely to develop heart failure than people without HIV, and people aged 40 or younger, women, or of Asian or Pacific Island origin were most at risk. risk.

“As far as young people are concerned, it is possible that they would have fewer other complicated health problems, which made the heart failure stand out,” said study lead author Alan S. Go, MD, Principal Investigator in the Research Division.

“In women, preliminary data suggests that HIV may have a greater impact on their heart function than in men, in part due to hormonal regulation and increased myocardial fibrosis, but this needs to be investigated. further. And, overall, little is known about heart problems and HIV in Asians and Pacific Islanders. “

The scans explained whether a person had risk factors for heart disease or was taking medications to prevent heart problems. “Our study showed that the higher risk was not due to differences in access to care,” said Dr Go. “They were all receiving the highest quality care. “


The study also showed that the higher risk of heart failure was not due to people living with HIV having more risk factors for heart disease or simply having had more heart attacks. In fact, there was a higher prevalence of risk factors for cardiovascular disease in people without HIV, Dr. Go said.

The researchers said their study shows why it is important for people living with HIV and their health care providers to know that shortness of breath, fatigue, swelling in the legs, cough and chest pain can be symptoms. signs of early heart failure. “HIV patients often receive all of their care in busy primary care HIV clinics, and signs and symptoms of heart failure may go unrecognized, resulting in treatment delays.” , Silverberg said.


Kaiser Permanente has been at the forefront of the fight against heart disease in people living with HIV. “An early study from Kaiser Permanente Northern California was among the first to show that people living with HIV are at a higher risk of cardiovascular disease,” said Silverberg, adding, “So we are aware of heart problems in this context. since a while. for a long time and our patients have received excellent preventive care.

Despite this, we still see a higher risk of heart failure, and we need more research to understand why so that we can intervene sooner. “

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